Sheldon J. Plankton (voice)

Plankton / Larry / Fred / Various Incidental Characters (voice)

Plankton / Teen Plankton / Rube / Snorkler (voice)

Larry the Lobster

Plankton / Larry the Lobster / Anchovy #1 / Sea Bunnies / Sea Urchins (voice)

Fred / Larry / Plankton / Video Announcer / Plankton Lincoln / Snail Walker / Bottomite Crowd (voice)

Xanadome Announcer

Plankton / PlankBot / Rube / Rubedor / Robo-Larry

Plankton (voice)

Plankton (voice)

Self (As Doug Lawrence)

Filburt / Maitre D' / Martian 1 / Doug / Hopping Hessian / Doodleberg / Lizard (voice)

Plankton / Potty / Rube / Larry / Fred / Charleston / Robber

Plankton / Buff Ghost / Ghost (voice)

Plankton / Buff Ghost / Ghost (voice)

Larry the Lobster / Fish (voice)

Old Lady / Genie of the Aluminum Anus (voice)

Plankton / Plankton Robot / News Anchor Fish / Mob Member (voice)

Plankton

Plankton (voice)