Spot Helperman / Scott Leadready II / Scott Manly-Manning (voice)

Dr. Ivan Krank (voice)

Leonard Amadeus Helperman (voice)

Mrs. Mary Lou Moira Angela Darling Helperman (voice)

Mr. Jolly (voice)

Pretty Boy (voice)

Dennis (voice)

Adele (voice)

Principal Crosby Strickler (voice)

Ian Wazselewski (voice)